Pronunciation: (krôs'ri-zis'tuns, kros'-), [key]
n. Biol.
1. immunologic resistance to the pathogenic effects of a microorganism because of previous exposure to another species or type having cross-reactive antigens.
2. resistance to the effects of a substance, as that of an insect population to an insecticide or a bacterial strain to an antibiotic, stimulated by exposure and adaptation to a similar or related substance.

Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.

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