Dictionary![]() ![]() down•streamPronunciation: (doun'strēm'), [key] —adv. with or in the direction of the current of a stream. —adj. 1. of or pertaining to the latter part of a process or system. 2. Genetics.with or in the direction of transcription, translation, or synthesis of a DNA, RNA, or protein molecule. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.
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