Dictionary![]() ![]() lo•coPronunciation: (lō'kō), [key] —n., pl. -cos, —v., -coed, -co•ing, —adj. —n. 1. locoweed. 2. Slang.an insane person; maniac. 3. Vet. Pathol.locoism. —v.t. 1. to poison with locoweed. 2. Slang.to cause to be insane or crazy. —adj. Slang.out of one's mind; insane; crazy. Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.
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