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Dictionary

perni'cious ane'mia

Pathol.
a severe anemia caused by the diminution or absence of stomach acid secretion, with consequent failure of the gastric mucosa to secrete the intrinsic factor necessary for the absorption of vitamin B₁₂, characterized by a great reduction in the number of red blood cells and an increase in their size.

Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.

pernicious

pernickety

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