Dictionary![]() ![]() San•ta CruzPronunciation: (san'tu krOOz'; for 3 also Sp. sän'tä krOOs'), [key] 1. a city on the coast of California. 41,483. 2. an island in NW Santa Barbara Islands. 3. a city in central Bolivia. 149,230. 4. See St. Croix (def. 1). Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.
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