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Down' syn'drome

a genetic disorder, associated with the presence of an extra chromosome 21, characterized by mild to severe mental retardation, weak muscle tone, a low nasal bridge, and epicanthic folds at the eyelids. Also,Down's syndrome.Formerly, mongolism. Also called trisomy 21.

Random House Unabridged Dictionary, Copyright © 1997, by Random House, Inc., on Infoplease.

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